Electroretinogram abnormalities in FKRP-related limb-girdle muscular dystrophy (LGMDR9).

Joshua L HagedornTaylor M DunnSajag BhattaraiCarrie StephanKatherine D MathewsWanda PfeiferArlene V Drack

Published in: Documenta ophthalmologica. Advances in ophthalmology (2022)

Abnormal ON/OFF bipolar cell responses and sawtooth 30 Hz flicker waveforms on full-field electroretinogram may be specific for LGMDR9. If confirmed in a larger population and if related to disease stage, these tests are potential biomarkers which could be useful as endpoints in clinical treatment trials.

Keyphrases

muscular dystrophy
duchenne muscular dystrophy
single cell
cell therapy
mesenchymal stem cells
bone marrow
combination therapy
smoking cessation
drug induced