Absence of Intestinal Microbiota during Gestation and Lactation Does Not Alter the Metabolic Response to a Western-type Diet in Adulthood.
Mirjam A M LohuisCornelieke C N WerkmanHermie J M HarmsenUwe J F TietgeHenkjan J VerkadePublished in: Molecular nutrition & food research (2018)
A germ-free status during gestation and lactation does not substantially affect key parameters of the metabolic status before 10 weeks of age on chow diet or in adulthood following a WTD challenge. These data imply that microbiota in early life does not critically affect adult metabolic plasticity.