Diffusion Tensor Imaging in Boys With Adrenoleukodystrophy: Identification of Cerebral Disease and Association With Neurocognitive Outcomes.
Elizabeth I PierpontRené LabounekAshish O GuptaTroy C LundPaul J OrchardWilliam B DobynsMonica BondyAmy PaulsonAndrew MetzRyan ShanleyJeffrey R WozniakBryon A MuellerDaniel LoesDavid NasceneIgor NestrašilPublished in: Neurology (2024)
DTI was sensitive to lesion presence and severity as well as clinical neurocognitive effects of C-ALD. DTI metrics quantify C-ALD even at an early stage.