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Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus.

Safaa Abdel-Aal Mohamed Abdel-KarimAmira Mohamed Ali El-GaninyMona Abdelmonem El-SayedHisham Abdelmonem Abdelhamid Abbas
Published in: PloS one (2022)
Diclofenac sodium, domperidone and glyceryl trinitrate showed higher efflux inhibitory activities than verapamil and metformin. To our knowledge, this is the first report that shows that diclofenac sodium, glyceryl trinitrate and domperidone have efflux pump inhibitory activities against S. aureus.
Keyphrases
  • staphylococcus aureus
  • healthcare
  • pseudomonas aeruginosa