Brucella ovis mutant in ABC transporter protects against Brucella canis infection in mice and it is safe for dogs.

Camila EcksteinJuliana P S MolFabíola B CostaPhilipe P NunesPâmela A LimaMarília M MeloThaynara P CarvalhoDaniel O SantosMonique F SilvaTatiane F CarvalhoLuciana F CostaOtoni A O Melo JúniorRodolfo C GiunchetteTatiane A PaixãoRenato de Lima Santos

Published in: PloS one (2020)

Encapsulated BoΔabcBA protected mice against experimental B. canis infection, and it is safe for dogs. Therefore, B. ovis ΔabcBA has potential as a vaccine candidate for canine brucellosis prevention.

Keyphrases

high fat diet induced
wild type
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insulin resistance
risk assessment
human health
climate change
adipose tissue