Effect of Celastrus orbiculatus in inhibiting Helicobacter pylori induced inflammatory response by regulating epithelial mesenchymal transition and targeting miR-21/PDCD4 signaling pathway in gastric epithelial cells.
Yao-Dong ZhuLei LiuLei HuWenqing DongMei ZhangYanqing LiuPing LiPublished in: BMC complementary and alternative medicine (2019)
COE inhibits H. pylori induced inflammatory response through regulating EMT, correlating with inhibition of miR-21/PDCD4 signal pathways in gastric epithelial cells.
Keyphrases
- inflammatory response
- epithelial mesenchymal transition
- helicobacter pylori
- signaling pathway
- cell proliferation
- long non coding rna
- high glucose
- lipopolysaccharide induced
- diabetic rats
- long noncoding rna
- transforming growth factor
- helicobacter pylori infection
- lps induced
- toll like receptor
- pi k akt
- endothelial cells
- cancer therapy
- drug delivery
- induced apoptosis
- stress induced