Influence of Age on the Diagnosis of Myocardial Infarction.
Matthew T H LowryDimitrios DoudesisRyan WereskiDorien M KimenaiChristopher TuckAmy V FerryAnda BulargaCaelan TaggartKuan K LeeNicholas L MillsAnoop S V ShahDavid E NewbyNicholas L MillsAtul Anandnull nullPublished in: Circulation (2022)
Age alters the diagnostic performance of cardiac troponin, with reduced specificity and positive predictive value in older patients when applying the guideline-recommended or age-adjusted 99th centiles. Individualized diagnostic approaches rather than the adjustment of binary thresholds are needed in an aging population.