Incidence and characteristics of pseudoprogression in IDH-mutant high-grade gliomas: a POLA network study.

Antoine SeyveCaroline DehaisOlivier ChinotApolline DjeladElisabeth Cohen-MoyalCharlotte BronnimannCarole GourmelonEvelyne EmeryPhilippe ColinMathieu BooneElodie VauléonOlivier LangloisAnna-Luisa di StefanoRomuald SeizeurFrançois GhiringhelliAnne D'HombresLoic FeuvretJacques GuyotatLaurent CapelleCatherine CarpentierLouis GarnierJérôme HonnoratDavid MeyronetKarima MokhtariDominique Figarella BrangerFrançois Ducraynull null

Published in: Neuro-oncology (2022)

In patients with an IDHmt HGG, pseudoprogression occurs later than in IDH-wildtype glioblastomas and seems not only frequent but also frequently misdiagnosed. Within the first 2 years after radiotherapy, the possibility of a pseudoprogression should be carefully considered.

Keyphrases

high grade
low grade
wild type
early stage
risk factors
radiation therapy
locally advanced
rectal cancer