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A novel in vivo model of puncture-induced iris neovascularization.

Ophélie BeaujeanFilippo LocriMonica AronssonAnders KvantaHelder André
Published in: PloS one (2017)
This study presents the first evidence of a puncture-induced iris angiogenesis model in the mouse. In a broader context, this novel in vivo model of neovascularization has the potential for noninvasive evaluation of angiogenesis modulating substances.
Keyphrases
  • vascular endothelial growth factor
  • high glucose
  • endothelial cells
  • diabetic rats
  • diabetic retinopathy
  • drug induced
  • signaling pathway
  • ultrasound guided
  • oxidative stress
  • climate change
  • wound healing