A novel in vivo model of puncture-induced iris neovascularization.

Ophélie BeaujeanFilippo LocriMonica AronssonAnders KvantaHelder André

Published in: PloS one (2017)

This study presents the first evidence of a puncture-induced iris angiogenesis model in the mouse. In a broader context, this novel in vivo model of neovascularization has the potential for noninvasive evaluation of angiogenesis modulating substances.

Keyphrases

vascular endothelial growth factor
high glucose
endothelial cells
diabetic rats
diabetic retinopathy
drug induced
signaling pathway
ultrasound guided
oxidative stress
climate change
wound healing