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Impaired antioxidant KEAP1-NRF2 system in amyotrophic lateral sclerosis: NRF2 activation as a potential therapeutic strategy.

Silvia BonoMarco FeligioniMassimo Corbo
Published in: Molecular neurodegeneration (2021)
Although challenges associated with some of these compounds remain, important advances have been made in the development of safer and more effective drugs that could actually represent a breakthrough for fatal degenerative diseases such as ALS.
Keyphrases
  • oxidative stress
  • anti inflammatory
  • amyotrophic lateral sclerosis
  • drug induced