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Left Main Coronary Artery Calcium and Diabetes Confer Very-High-Risk Equivalence in Coronary Artery Calcium >1,000.

Alexander C RazaviLeslee J ShawDaniel S BermanMatthew J BudoffNathan D WongViola VaccarinoMarly van AssenCarlo N De CeccoArshed A QuyyumiAnurag MehtaPaul MuntnerMichael D MiedemaAlan RozanskiJohn A RumbergerKhurram NasirRoger S BlumenthalLaurence S SperlingMartin Bødtker MortensenSeamus P WheltonMichael J BlahaOmar Dzaye
Published in: JACC. Cardiovascular imaging (2024)
Among asymptomatic patients with a CAC of ≥1,000 without a prior index event, diabetes, and severe LM CAC define very high risk ASCVD, identifying individuals who may benefit from more intensive prevention therapies across several domains, including low-density lipoprotein-cholesterol lowering.
Keyphrases
  • coronary artery
  • pulmonary artery
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • early onset
  • adipose tissue
  • pulmonary hypertension
  • insulin resistance
  • weight loss
  • skeletal muscle