Cellular Mass Response to Therapy Correlates With Clinical Response for a Range of Malignancies.
Mark M StevensRobert J KimmerlingSelim OlcumMadeleine VachaRachel LaBellaAnthony MinnahKatelin KatsisJuanita FujiiZayna ShaheenSrividya SundaresanJoseph CriscitielloRuben NiesvizkyNoopur S RajeAndrew R BranaganAmrita Y KrishnanSundar JagannathSamir S ParekhAdam S SperlingCara A RosenbaumNikhil C MunshiMarlise R LuskinAnobel TamraziClifford A ReidPublished in: JCO precision oncology (2024)
MRT showed highly significant correlation with clinical response to therapy. Routine clinical use is technically feasible and broadly applicable to a wide range of samples and malignancy types, supporting the need for future validation studies.