Decision-making impairment under ambiguity but not under risk may underlie medication overuse in patients with chronic migraine.
Chi Ieong LauWei-Hung ChenHan-Cheng WangVincent WalshPublished in: Headache (2023)
Our data suggest that patients with CM + MOH had impaired decisions under ambiguous, but not risky situations. This dissociation indicates disrupted emotional feedback processing rather than executive dysfunction, which may underlie the pathogenesis of MOH.