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Nestorone® , a 19nor-progesterone derivative boosts remyelination in an animal model of demyelination.

Martine El-EtrYvette AkwaMarion RameMichael SchumacherRégine Sitruk-Ware
Published in: CNS neuroscience & therapeutics (2020)
NES alone or with E2 increased the levels of transcription factors, essential for myelin synthesis.
Keyphrases
  • transcription factor
  • white matter
  • estrogen receptor
  • dna binding
  • water soluble
  • multiple sclerosis