Nestorone® , a 19nor-progesterone derivative boosts remyelination in an animal model of demyelination.
Martine El-EtrYvette AkwaMarion RameMichael SchumacherRégine Sitruk-WarePublished in: CNS neuroscience & therapeutics (2020)
NES alone or with E2 increased the levels of transcription factors, essential for myelin synthesis.