[The balance of proinflammatory cytokines and Treg cells in chronic glomerulonephritis].

Natalia V Chebotareva A A Vinogradov Alla GindisI N BobkovaWenjing Cao L V Lysenko

Published in: Terapevticheskii arkhiv (2020)

An imbalance of cytokines characterized by an increased levels of pro-inflammatory IL-17, IL-6, TNF-a, and a reduced levels of anti-inflammatory IL-10 and T-regulatory cells in the kidney tissue is noted in patients with NS, especially with FSGS. Imbalance of cytokines reflects the high activity of CGN and the risk of the progression of the disease.

Keyphrases

induced apoptosis
cell cycle arrest
anti inflammatory
rheumatoid arthritis
oxidative stress
cell death