Atrial fibrillation and its arrhythmogenesis associated with insulin resistance.
Yi-Hsin ChanGwo-Jyh ChangYing-Ju LaiWei-Jan ChenShang-Hung ChangLi-Man HungChi-Tai KuoYung-Hsin YehPublished in: Cardiovascular diabetology (2019)
IR engenders both atrial structural remodeling and abnormal intracellular calcium homeostasis, contributing to increased AF susceptibility. The inhibition of CaMKII may be a potential therapeutic target for AF in insulin resistance.
Keyphrases
- atrial fibrillation
- insulin resistance
- catheter ablation
- left atrial
- adipose tissue
- oral anticoagulants
- high fat diet
- metabolic syndrome
- polycystic ovary syndrome
- skeletal muscle
- left atrial appendage
- direct oral anticoagulants
- type diabetes
- high fat diet induced
- heart failure
- percutaneous coronary intervention
- glycemic control
- weight loss
- venous thromboembolism
- climate change