Severe atopic dermatitis, sleep disturbance, and low light exposure.

Mariam K ArifPhyllis C ZeeAmy S PallerStephanie J CrowleyTill RoennebergAnna B Fishbein

Published in: Sleep (2023)

Severe AD is characterized by low RLE and sleep disturbance. Low RLE could potentially induce circadian misalignment, contributing to inflammation and worse disease in severe AD. Low RLE can also reflect altered lifestyle and behavior due to atopic disease burden. Prospective studies are needed to test causality and the potential of bright light as an adjuvant therapy for severe AD.

Keyphrases

early onset
atopic dermatitis
physical activity
metabolic syndrome
cardiovascular disease
early stage
type diabetes
risk factors
climate change
risk assessment