Maternal soluble PD-1 levels are significantly increased in women with preeclampsia.

Yang GuJohn MorganDavid F LewisDanielle B CooperCharles E McCathranYuping Wang

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)

Aberrant sPD-1/sPD-L1 signaling is present in preeclampsia. Whether increased maternal sPD-1 and sPD-L1 levels were associated with fetal gender difference or immune tolerance dissimilarity during pregnancy in women with preeclampsia warrants further investigation.

Keyphrases

pregnancy outcomes
early onset
pregnant women
birth weight
mental health
body mass index