The Impact of Dose Reduction of Bacillus Calmette-Guerin on Oncological Outcomes and Toxicity in Non-Muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis.
Wadi AzuriJorge Horacio JaunarenaJuan Jorge CameanJoaquín ChemiAlberto VillarongaSiamak DaneshmandGustavo Martín VilloldoPublished in: Bladder cancer (Amsterdam, Netherlands) (2023)
Dose reduction did not affect the oncological outcomes of patients with NMIBC who received adjuvant therapy with BCG. On the other hand, dose reduction showed a significant trend towards fewer systemic and local side effects. Further studies comparing oncological and toxicity outcomes using different strains are needed.