Selective Oxidative Dearomatization of Angular Tetracyclic Phenols by Controlled Irradiation under Air: Synthesis of an Angucyclinone-Type Double Peroxide with Anticancer Properties.

María J Cabrera-AfonsoSilvia R LucenaÁngeles JuarranzAntonio UrbanoM Carmen Carreño

Published in: Organic letters (2018)

Angular tetracyclic p-peroxyquinols, p-quinols, and a pentacyclic double peroxide, showing anticancer properties, were synthesized from the corresponding phenols by an environmentally friendly solvent- and wavelength-controlled irradiation under air in the absence of an external photosensitizer.

Keyphrases

photodynamic therapy
radiation induced
ionic liquid
radiation therapy
low cost