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Causal association between obesity, circulating glutamine levels, and depression: a Mendelian randomization study.

Ruixin HeRuizhi ZhengJie ZhengMian LiTian-Ge WangZhi-Yun ZhaoShuangyuan WangHong LinJie-Li LuYuhong ChenYu XuWei-Qing WangYanan HouYu-Fang BiYanqiu Wang
Published in: The Journal of clinical endocrinology and metabolism (2022)
The present study reported that higher BMI was causally associated with lower glutamine levels. Both obesity and down-regulation of glutamine were causally linked to depression.
Keyphrases
  • metabolic syndrome
  • insulin resistance
  • type diabetes
  • weight loss
  • weight gain
  • body mass index
  • adipose tissue
  • skeletal muscle