Intracerebroventricular injection of propranolol blocked analgesic and neuroprotective effects of resveratrol following L5 spinal nerve ligation in rat.

Mohammad Ali ZabihianMehdi HosseiniFarideh BahramiMaryam ImanMaedeh GhasemiMohammad Taghi MohammadiZahra Bahari

Published in: Journal of complementary & integrative medicine (2021)

It is suggested that the analgesic effects of resveratrol is mediated by its neuroprotective and antioxidant activities in the neuropathic rats. Furthermore, propranolol blocked the analgesic and neuroprotective effects of resveratrol.

Keyphrases

anti inflammatory
cerebral ischemia
neuropathic pain
spinal cord
oxidative stress
subarachnoid hemorrhage
spinal cord injury
brain injury
blood brain barrier