Subtype-Specific Association of Mitochondrial DNA Copy Number With Poststroke/TIA Outcomes in 10 241 Patients in China.
Yi JiangSi ChengYanfeng ShiZhe XuHuihui WangYanran LiYang LiuZi-Xiao LiYong JiangXia MengShanShan ChengHao LiChaolong WangYong-Jun WangPublished in: Stroke (2024)
Lower mtDNA-CN is associated with higher stroke recurrence rate and all-cause mortality, as well as poorer functional outcome at follow-up, among stroke of undetermined cause, embolic stroke of undetermined source, and younger patients.
Keyphrases
- mitochondrial dna
- copy number
- end stage renal disease
- atrial fibrillation
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- genome wide
- squamous cell carcinoma
- type diabetes
- metabolic syndrome
- patient reported outcomes
- skeletal muscle
- insulin resistance
- weight loss
- brain injury
- glycemic control