Discovery of new Schistosoma mansoni aspartyl protease inhibitors by structure-based virtual screening.
Bárbara Figueira GomesMario Roberto SengerJosé Teófilo Moreira-FilhoFabio Jorge de Vasconcellos JuniorRafael Ferreira DantasRaymond OwensCarolina Horta AndradeBruno Junior NevesFloriano Paes Silva-JrPublished in: Memorias do Instituto Oswaldo Cruz (2023)
Overall, the inhibitors identified in this work represent promising hits for further hit-to-lead optimisation.
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