A Model for Studying the Biomechanical Effects of Varying Ratios of Collagen Types I and III on Cardiomyocytes.

Brian Roman Shweta Anil Kumar Shane C Allen Monica DelgadoSabastian MoncayoAndres M ReyesLaura J Suggs Ramana Chintalapalle Chunqiang Li Binata Joddar

Published in: Cardiovascular engineering and technology (2021)

This study model can be adopted to simulate various biomechanical environments in which cells crosstalk with the Collagen-matrix in diseased pathologies to generate insights on strategies for prevention of fibrosis.

Keyphrases

induced apoptosis
cell cycle arrest
tissue engineering
finite element analysis
cell death
signaling pathway
endoplasmic reticulum stress