Arterial spin labeling provides a reliable neurobiological marker of autism spectrum disorder.

Benjamin E YerysJohn D HerringtonGregory K BartleyHua-Shan LiuJohn A DetreRobert T Schultz

Published in: Journal of neurodevelopmental disorders (2018)

Arterial spin labeling revealed hypoperfusion in children with ASD in regions critical to social perception and cognition. The left fusiform gyrus plays an important role in facial recognition, and greater CBF in this region was correlated with more normative facial recognition performance in children with ASD. This study takes an important first step in establishing CBF of the temporal lobes as a reliable marker of ASD.

Keyphrases

autism spectrum disorder
attention deficit hyperactivity disorder
intellectual disability
young adults
room temperature
density functional theory
healthcare
single molecule
cognitive impairment
white matter
transition metal
working memory