COVID-19: viral-host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection.

Francesco MessinaEmanuela GiombiniChiara AgratiFrancesco VairoTommaso Ascoli BartoliSamir Al MoghaziMauro PiacentiniFranco LocatelliGary KobingerMarkus MaeurerAlimuddin ZumlaMaria Rosaria CapobianchiFrancesco Nicola LauriaGiuseppe Ippolitonull null

Published in: Journal of translational medicine (2020)

In this paper, we developed a network-based model with the aim to define molecular aspects of pathogenic phenotypes in HCoV infections. The resulting pattern may facilitate the process of structure-guided pharmaceutical and diagnostic research with the prospect to identify potential new biological targets.

Keyphrases

sars cov
coronavirus disease
respiratory syndrome coronavirus
risk assessment
climate change