Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or 4.
Jean-Daniel LalauFarshad KajbafYoussef BennisAnne-Sophie Hurtel-LemaireFrans BelpaireMarc E De BroePublished in: Diabetes care (2018)
Provided that the dose is adjusted for renal function, metformin treatment appears to be safe and still pharmacologically efficacious in moderate-to-severe CKD.