Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Avidity Maturation and Association with Disease Severity.
Ruben Yiqi LuoIndrani ChakrabortyCassandra YunAlan H B WuKara L LynchPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
The kinetics of IgG avidity maturation during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was studied. The IgG avidity assay, using a novel label-free immunoassay technology, revealed a strong correlation between IgG avidity and days since symptom onset. Peak readings were significantly higher in severe than mild disease cases.