Aptamer-tagged DNA origami for spatially addressable detection of aflatoxin B1.

Zhi Song LuYing WangDan XuLei Pang

Published in: Chemical communications (Cambridge, England) (2018)

A DNA origami-based platform for detecting aflatoxin B1 has been constructed with the assistance of aptamer probes and its complementary ssDNA-modified gold nanoparticles. This work may open new horizons for the application of DNA origami in the detection of a variety of small molecules.

Keyphrases

gold nanoparticles
label free
single molecule
circulating tumor
loop mediated isothermal amplification
cell free
sensitive detection
real time pcr
nucleic acid
minimally invasive
small molecule
wastewater treatment
high throughput
living cells
magnetic nanoparticles
single cell