Cortical and subcortical morphometric changes and their relation to cognitive impairment in isolated REM sleep behavior disorder.

Christiane Malá Filip Havlik Josef Mana Jiří Nepožitek Simona Dostálová Evžen Růžička Karel Sonka Jiří Keller Robert Jech Petr Dušek Ondrej Bezdicek Radim Krupička

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)

iRBD shows deficits in several cognitive tests that correlate with morphological changes, the most prominent of which is in psychomotor speed and visual attention as measured by the TMT-A and associated with the volume of striatum, insula, cerebellum, temporal lobe, pallidum and amygdala.

Keyphrases

functional connectivity
cognitive impairment
resting state
prefrontal cortex
working memory
traumatic brain injury
sleep quality
white matter
physical activity