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No Evidence for a Causal Link between Serum Uric Acid and Nonalcoholic Fatty Liver Disease from the Dongfeng-Tongji Cohort Study.

Yuhan TangYanyan XuPeiyi LiuCheng LiuRong ZhongXiao YuLin XiaoMin DuLing YangJing YuanYoujie WangWeihong ChenSheng WeiYuan LiangXiaomin ZhangTangchun WuMeian HeXiaoping MiaoPing Yao
Published in: Oxidative medicine and cellular longevity (2022)
SUA was positively associated with NAFLD incidence especially in female and normal-weight individuals and the suspected progression risk of newly developed NAFLD. However, the Mendelian randomization analyses lend no causal evidence, suggesting high SUA as a marker and not a cause of NAFLD.
Keyphrases
  • uric acid
  • metabolic syndrome
  • physical activity
  • risk factors
  • weight loss