Comparison of the clinical effectiveness and safety between the use of denosumab vs bisphosphonates in renal transplant patients.
Hayley McKeeG IoannidisA LauD TreleavenA GangjiC RibicM Wong-PackA PapaioannouJ D AdachiPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2020)
Both treatments increased lumbar spine BMD; however, the effect of denosumab was greater compared with that of bisphosphonate treatment. Our study provides evidence for the efficacy of denosumab treatment in renal transplant patients. Caution around hypocalcemia is warranted. We recommend more prospective studies to analyze the effects of long-term antiresorptive therapy in patients with a renal transplant.