Different modulation effects of 1 Hz and 20 Hz transcutaneous auricular vagus nerve stimulation on the functional connectivity of the periaqueductal gray in patients with migraine.

Jin CaoYue ZhangHui LiZhaoxian YanXian LiuXiaoyan HouWeicui ChenSierra HodgesJian KongBo Liu

Published in: Journal of translational medicine (2021)

Our findings suggest that taVNS with different frequencies may produce different modulation effects on the descending pain modulation system, demonstrating the important role of stimulation frequency in taVNS treatment.

Keyphrases

functional connectivity
resting state
chronic pain
pain management
neuropathic pain
smoking cessation