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Enhancing thalassemia gene carrier identification in non-anemic populations using artificial intelligence erythrocyte morphology analysis and machine learning.

Fan ZhangJieyu ZhanYang WangJing ChengMeinan WangPei-Song ChenJuan OuyangJun-Xun Li
Published in: European journal of haematology (2023)
The ML-based model TT@Normal could efficiently identify TT carriers in non-anemic people. Elevated percentages of target cells, microcytes, and teardrop cells should raise a strong suspicion of being a TT gene carrier.
Keyphrases
  • artificial intelligence
  • machine learning
  • induced apoptosis
  • big data
  • cell cycle arrest
  • deep learning
  • copy number
  • genome wide
  • endoplasmic reticulum stress
  • oxidative stress
  • genome wide identification