High frequency of disease progression in pediatric spinal cord low-grade glioma (LGG): management strategies and results from the German LGG study group.
Thomas PerweinMartin BeneschDaniela KandelsTorsten PietschRené SchmidtFranz QuehenbergerBrigitte BisonMonika Warmuth-MetzBeate TimmermannJürgen KraussUlrich Wilhelm ThomaleRolf-Dieter KortmannPablo Hernáiz DrieverAstrid Katharina GnekowPublished in: Neuro-oncology (2021)
The majority of patients experienced disease progression, even after years. Multiple interventions were required for more than a third, yet multimodal treatment enabled long-term disease control. Molecular testing may reveal therapeutic targets.