MitoFish, MitoAnnotator, and MiFish Pipeline: Updates in 10 Years.
Tao ZhuYukuto SatoTetsuya SadoMasaki MiyaWataru IwasakiPublished in: Molecular biology and evolution (2023)
MitoFish, MitoAnnotator, and MiFish Pipeline are comprehensive databases of fish mitochondrial genomes (mitogenomes), accurate annotation software of fish mitogenomes, and a web platform for metabarcoding analysis of fish mitochondrial environmental DNA (eDNA), respectively. The MitoFish Suite currently receives over 48,000 visits worldwide every year; however, the performance and usefulness of the online platforms can still be improved. Here, we present essential updates on these platforms, including an enrichment of the reference data sets, an enhanced searching function, substantially faster genome annotation and eDNA analysis with the denoising of sequencing errors, and a multisample comparative analysis function. These updates have made our platform more intuitive, effective, and reliable. These updated platforms are freely available at http://mitofish.aori.u-tokyo.ac.jp/.
Keyphrases
- oxidative stress
- high throughput
- big data
- rna seq
- single cell
- data analysis
- social media
- machine learning
- healthcare
- genome wide
- patient safety
- circulating tumor
- electronic health record
- gene expression
- health information
- dna methylation
- mass spectrometry
- human health
- artificial intelligence
- climate change
- life cycle
- nucleic acid