Hand-mixed vancomycin versus commercial tobramycin cement revisited: A study on mechanical and antibacterial properties.
Vivek Ajit SinghBong Chun HawAmber HaseebCindy Shuan Ju TehPublished in: Journal of orthopaedic surgery (Hong Kong) (2020)
It was effectively concluded that HMAC is advantageous as a cement spacer; however, it is not recommended for primary arthroplasty and second-stage revision arthroplasty. The recommended maximum concentration of vancomycin based on this study is 2 g/pack (40 g) of cement. Industrial preblended antibiotic cement is superior to hand-mixed cement.