Genomic profiling of intestinal/mixed-type superficial non-ampullary duodenal epithelial tumors.

Shuichi Miyamoto Goki SudaMarin IshikawaHideyuki HayashiSatoshi NimuraYoshihiro MatsunoRyo MoriShigeki TanishimaTakahiko KudoTomofumi TakagiYoshiya YamamotoShoko OnoYuichi ShimizuNaoya Sakamoto

Published in: JGH open : an open access journal of gastroenterology and hepatology (2021)

We detected APC alterations in most small SNADETs resected via endoscopic treatment, from LGD to carcinoma samples. Even in SNADETs classified as small LGD exhibited KRAS and BRAF alterations.

Keyphrases

wild type
ultrasound guided
lymph node
single cell
copy number
gene expression
combination therapy
dna methylation
metastatic colorectal cancer