Disrupted rich club organization and structural brain connectome in unmedicated bipolar disorder.

Ying WangFeng DengYanbin JiaJunjing WangShuming ZhongHuiyuan HuangLixiang ChenGuanmao ChenHuiqing HuLi HuangRuiwang Huang

Published in: Psychological medicine (2018)

Our results may reflect the disrupted white matter topological organization in the whole-brain, and abnormal regional connectivity supporting cognitive and affective functioning in depressed BD, which, in part, be due to impaired rich club connectivity.

Keyphrases

resting state
bipolar disorder
functional connectivity
white matter
major depressive disorder
multiple sclerosis