Untargeted characterisation of dissolved organic matter contributions to rivers from anthropogenic point sources using direct-infusion and high-performance liquid chromatography/Orbitrap mass spectrometry.
Jonathan A PembertonCharlotte E M LloydChristopher J ArthurPenny J JohnesMichael DickinsonAdrian J CharltonRichard P EvershedPublished in: Rapid communications in mass spectrometry : RCM (2020)
This new approach enables comprehensive analysis of DOM in extracts without any preconceived ideas of the compounds which may be present. This approach has the potential to be used as a high throughput, qualitative, screening method to determine if the composition of point sources differs from that of the receiving water bodies, providing a new approach to the identification of hitherto unrecognised organic contribution to water bodies.
Keyphrases
- mass spectrometry
- high performance liquid chromatography
- liquid chromatography
- tandem mass spectrometry
- high throughput
- ultra high performance liquid chromatography
- drinking water
- high resolution mass spectrometry
- gas chromatography
- simultaneous determination
- capillary electrophoresis
- solid phase extraction
- high resolution
- low dose
- systematic review
- organic matter
- single cell
- ms ms
- human health
- risk assessment
- bioinformatics analysis