Interleukin-8 release by endothelial colony-forming cells isolated from idiopathic pulmonary fibrosis patients might contribute to their pathogenicity.
Adeline BlandinièresNicolas GendronNour BachaIvan BiècheRichard ChocronHilario NunesNathalie NevoElisa RossiBruno CrestaniSéverine LecourtSylvie ChevretAnna LokajczykVirginie MignonAlexandre KisaogluKarine JuvinSebastien BertilDominique ValeyreAudrey CrasPascale GaussemDominique Israël-BietDavid M SmadjaPublished in: Angiogenesis (2019)
To conclude, our study shows that IPF patients have a senescent ECFC phenotype associated with an increased IL-8 secretion potential that might contribute to lung neutrophils invasion during IPF.