Is High Expression of Claudin-7 in Advanced Colorectal Carcinoma Associated with a Poor Survival Rate? A Comparative Statistical and Artificial Intelligence Study.
Victor IanoleMihai DanciuConstantin VolovatCipriana StefanescuPaul-Corneliu HerghelegiuFlorin LeonAdrian IfteneCiprian-Gabriel CusmuliucBogdan TomaVasile DrugDelia Gabriela Apostol CiobanuPublished in: Cancers (2022)
The study showed through statistical means that the immunohistochemical overexpression of Claudin-7 in the tumor invasive front may represent a poor prognostic factor in advanced stages of CRCs, contrary to AI models which could not predict the same outcome, probably because of the small number of patients included in our cohort.