Intraoperative electron beam radiotherapy and perioperative high-dose-rate brachytherapy in previously irradiated oligorecurrent gynecological cancer: clinical outcome analysis.
Paola Anna JablonskaM CambeiroM GimenoJ M AramendíaJ A MínguezJ L AlcázarJ J AristuF A CalvoR Martínez-MongePublished in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2021)
IOERT and PHDRB account for an effective salvage in oligorecurrent gynecological tumors. Patients with previous pelvic radiation suitable for salvage surgery and at risk of inadequate margins could benefit from adjuvant reirradiation in form of IOERT or PHDRB. However, the rate of severe grade ≥ 3 toxicity associated with the entire treatment program is relevant and needs to be closely counterbalanced against the expected therapeutic gain.
Keyphrases
- high dose
- early stage
- low dose
- stem cell transplantation
- radiation therapy
- minimally invasive
- patients undergoing
- papillary thyroid
- locally advanced
- rectal cancer
- radiation induced
- coronary artery bypass
- oxidative stress
- quality improvement
- cardiac surgery
- squamous cell
- electron microscopy
- coronary artery disease
- combination therapy
- lymph node metastasis
- monte carlo
- drug induced