Diffuse reflectance spectroscopy of the spine: improved breach detection with angulated fibers.
Merle S LoschFamke KarduxJenny DankelmanBenno H W HendriksPublished in: Biomedical optics express (2023)
Accuracy in spinal fusion varies greatly depending on the experience of the physician. Real-time tissue feedback with diffuse reflectance spectroscopy has been shown to provide cortical breach detection using a conventional probe with two parallel fibers. In this study, Monte Carlo simulations and optical phantom experiments were conducted to investigate how angulation of the emitting fiber affects the probed volume to allow for the detection of acute breaches. Difference in intensity magnitude between cancellous and cortical spectra increased with the fiber angle, suggesting that outward angulated fibers are beneficial in acute breach scenarios. Proximity to the cortical bone could be detected best with fibers angulated at θ f = 45 ∘ for impending breaches between θ p = 0 ∘ and θ p = 45 ∘ . An orthopedic surgical device comprising a third fiber perpendicular to the device axis could thus cover the full impending breach range from θ p = 0 ∘ to θ p = 90 ∘ .
Keyphrases
- monte carlo
- high resolution
- liver failure
- loop mediated isothermal amplification
- label free
- real time pcr
- respiratory failure
- low grade
- single molecule
- primary care
- quantum dots
- aortic dissection
- bone mineral density
- molecular dynamics
- hepatitis b virus
- solid state
- high speed
- mass spectrometry
- body composition
- image quality
- density functional theory
- bone loss