Bovine bone particulates containing bone anabolic factors as a potential xenogenic bone graft substitute.

David S MussonRyan GaoMaureen WatsonJian-Ming LinYoung-Eun ParkDonna TuariKaren E CallonMark ZhuNicola DalbethDorit NaotJacob T MunroJillian Cornish

Published in: Journal of orthopaedic surgery and research (2019)

Overall, despite the positive effects of the BBMPs on the cells of the bone, the bovine bone product as a whole did not enhance bone healing. Finding a way to harness the positive effect of these BBMPs would provide a clear benefit for healing bone non-union.

Keyphrases

bone mineral density
soft tissue
bone loss
bone regeneration
postmenopausal women
induced apoptosis
body composition
risk assessment
cell death
cell proliferation