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[Extracorporeal cytokine removal in chimeric antigen receptor T-cell therapy associated cytokine release syndrome in patient with acute lymphoblastic leukemia. Case report].

A E ShchekinaG M GalstyanO A GavrilinaN M ArapovaS I BronyakinaEkaterina KotovaV V TroitskayaElena N ParovichnikovaMikhail MaschanS M Kulikov
Published in: Terapevticheskii arkhiv (2021)
Сytokine release syndrome is the common complication of CAR-T therapy. We report a case of patient with B-cell acute lymphoblastic leukemia developing сytokine release syndrome with shock and multiple organ failure and requiring cytokine removal and hemodiafiltration. Remission of the disease was achieved after CAR-T therapy.
Keyphrases
  • case report
  • acute lymphoblastic leukemia
  • allogeneic hematopoietic stem cell transplantation
  • stem cells
  • acute myeloid leukemia
  • smoking cessation