Selective IgA Deficiency in Spontaneously Hypertensive Rats With Gut Dysbiosis.
Piu SahaBlair MellRachel M GolonkaVenugopal R BovillaAhmed A AbokorXue MeiBeng San YeohPeter A DorisAndrew T GewirtzBina JoeMatam Vijay-KumarPublished in: Hypertension (Dallas, Tex. : 1979) (2022)
This study is the first to reveal IgA deficiency in SHR as one host factor associated with gut microbiota dysbiosis and invigorates future research to determine the pathophysiological role of IgA in hypertension.