Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.

Kasey R KeeverKui CuiJared L CasteelSanjay SinghDonald B HooverDavid L WilliamsValentin A PavlovValentin P Yakubenko

Published in: Journal of neuroinflammation (2024)

We demonstrate a novel role for the α7nAChR in mediating macrophage recruitment to inflamed tissue, which indicates an important new aspect of the cholinergic regulation of immune responses and inflammation.

Keyphrases

oxidative stress
immune response
dendritic cells
liver failure
adipose tissue
drug induced
peripheral blood
hepatitis b virus
acute respiratory distress syndrome
extracorporeal membrane oxygenation