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Discrepancies in endpoints between clinical trial protocols and clinical trial registration in randomized trials in oncology.

Victoria J SerpasKanwal P RaghavDaniel M HalperinJames YaoMichael James Overman
Published in: BMC medical research methodology (2018)
Although recent regulations and enhanced procedures have improved the number and quality of clinical trial registrations, inconsistencies regarding endpoint reporting still exist. Though further guidelines for the registration of clinical trials will help, greater efforts to provide a correct, easily accessible, and complete representation of planned endpoints are needed.
Keyphrases
  • clinical trial
  • phase ii
  • open label
  • double blind
  • study protocol
  • phase iii
  • quality improvement
  • clinical practice
  • electronic health record